IGF-1 LR3

10MG

IGF-1 Receptor Signaling. Advanced Cellular Research.

IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid analogue of insulin-like growth factor 1 engineered with an Arg substitution at position 3 and a 13-amino-acid N-terminal extension. These changes markedly reduce binding to IGF-binding proteins while retaining activity at the IGF-1 receptor, making it useful for laboratory studies of growth-factor signaling, cell proliferation, survival and metabolic pathways. Human therapeutic benefits have not been established.

A Healthier Tomorrow

IGF-1 LR3

10MG

$100.00 — or Original price was: $100.00.Current price is: $90.00. / month

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IGF Signaling. Cellular Research.

IGF-1 LR3 (Long R3 IGF-1) is primarily used in laboratory and preclinical models to study IGF-1 receptor signaling and growth-related cellular pathways. Research has explored its effects on cell proliferation, survival and metabolism in cell culture and animal models. Human clinical efficacy and safety have not been established.

  • IGF-1 receptor activity
  • Reduced IGFB-binding protein interaction
  • Cell proliferation research
  • Muscle-cell signaling models
  • Metabolic pathways research

KEY AREAS OF HUMAN

KEY AREAS OF HUMAN

The Science

Evidence & Mechanism

Long R3 IGF-1 remains active at the IGF-1 receptor while showing greatly reduced affinity for IGF-binding proteins. In human fibroblast cell studies it produced stronger proliferative responses than native IGF-1, while most broader evidence comes from cell-culture and animal research. Human therapeutic safety and efficacy for IGF-1 LR3 have not been established.

IGF-1R

Reduced IGFBP Binding

PI3K–AKT Signaling

Cell Growth Signaling

Product Information

Product Name IGF-1 LR3 (Long R3 IGF-1)
Class 83-amino-acid IGF-1 analogue
Composition Native IGF-1 framework with Arg substitution at position 3 plus 13-amino-acid N-terminal extension
Strength 10 mg
Vial Size 3 mL
Purity Confirm per current batch COA
Product Format Lyophilized powder
Storage 2–8°C, dry, protected from light
Intended Use Laboratory research only. Not approved for human or veterinary use.

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FREQUENTLY ASKED QUESTIONS

Your Questions, Answered.

Find quick answers to common questions about this Product.

IGF-1 LR3 is a modified form of insulin-like growth factor 1 (IGF-1) designed with structural changes that affect its binding to IGF-binding proteins. It is primarily discussed in laboratory research investigating IGF-related signaling, cell growth, and metabolic processes. Research findings should not be interpreted as proof of safety or effectiveness in humans.

IGF-1 LR3 is studied in laboratory settings to investigate insulin-like growth factor signaling and its role in cellular growth, proliferation, and metabolism. Its research applications depend on the specific experimental model and study design. It is not approved as a treatment for human use.

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